Structure of PDB 8j6m Chain B Binding Site BS05

Receptor Information
>8j6m Chain B (length=641) Species: 6100 (Aequorea victoria) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGADFDHVYSGVVNLSTENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPV
LVVVRQQKEVLSWQVPLLFQGLYQRSYNYQEVSRTLCPSEATNETGPLQQ
LIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFTASPSQPQYFLYKF
PKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSMTKK
AAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFNLQRKKNLEVTIVPSIK
ESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKKYKIYFWNIITIAV
FYALPVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNLG
HVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPKHFGLFYAMGIALM
MEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASAYS
AYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYDRMVL
LVVGNLVNWSFALFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSS
EKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAESREKNRECILLD
FFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8j6m Chain B Residue 905 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8j6m SIDT1 protein
Resolution2.77 Å
Binding residue
(original residue number in PDB)		H563 D574 H791 H795
Binding residue
(residue number reindexed from 1)		H410 D421 H605 H609
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0015485 cholesterol binding
GO:0051033 RNA transmembrane transporter activity
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0008218 bioluminescence
GO:0050658 RNA transport
Cellular Component
GO:0005764 lysosome
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8j6m, PDBe:8j6m, PDBj:8j6m
PDBsum8j6m
PubMed38664565
UniProtQ9NXL6|SIDT1_HUMAN SID1 transmembrane family member 1 (Gene Name=SIDT1)

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