Structure of PDB 7qho Chain B Binding Site BS05

Receptor Information
>7qho Chain B (length=534) Species: 196627 (Corynebacterium glutamicum ATCC 13032) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSLATVGNNLDSRYTMASGIRRQINKVFPTHWSFMLGEIALYSFIVLLLT
GVYLTLFFDPSITKVIYDGGYLPLNGVEMSRAYATALDISFEVRGGLFIR
QMHHWAALLFVVSMLVHMLRIFFTGAFRRPREANWIIGVVLIILGMAEGF
MGYSLPDDLLSGVGLRIMSAIIVGLPIIGTWMHWLIFGGDFPSDLMLDRF
YIAHVLIIPAILLGLIAAHLALVWYQKHTQFPGAGRTENNVIGIRIMPLF
AVKAVAFGLIVFGFLALLAGVTTINAIWNLGPYNPSQVSAGSQPDVYMLW
TDGAARVMPAWELYLGNYTIPAVFWVAVMLGILVVLLVTYPFIERKFTGD
DAHHNLLQRPRDVPVRTSLGVMALVFYILLTVSGGNDVYAMQFHVSLNAM
TWIGRIGLIVGPAIAYFITYRLCIGLQRSDREVLEHGIETGIIKQMPNGA
FIEVHQPLGPVDDHGHPIPLPYAGAAVPKQMNQLGYAEVETRGGFFGPDP
EDIRAKAKEIEHANHIEEANTLRALNEANIERDK
Ligand information
Ligand IDLYC
InChIInChI=1S/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3/b12-11+,25-15+,26-16+,31-17+,32-18+,35-21+,36-22+,37-27+,38-28+,39-29+,40-30+
InChIKeyOAIJSZIZWZSQBC-GYZMGTAESA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0CC(=CCC/C(=C/C=C/C(=C/C=C/C(=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C=C(\C)/CCC=C(C)C)/C)/C)/C)C
CACTVS 3.341CC(C)=CCCC(C)=CC=CC(C)=CC=CC(C)=CC=CC=C(C)C=CC=C(C)C=CC=C(C)CCC=C(C)C
OpenEye OEToolkits 1.5.0CC(=CCCC(=CC=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC=C(C)CCC=C(C)C)C)C)C)C
CACTVS 3.341CC(C)=CCC\C(C)=C\C=C\C(C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C=C(/C)CCC=C(C)C
ACDLabs 10.04C(\C=C\C=C(\CC/C=C(\C)C)C)(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C=C(\C)CC\C=C(/C)C)C)C)C)C
FormulaC40 H56
NameLYCOPENE
ChEMBLCHEMBL501174
DrugBankDB11231
ZINCZINC000008214943
PDB chain7qho Chain B Residue 606 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7qho Structural basis for safe and efficient energy conversion in a respiratory supercomplex
Resolution3.1 Å
Binding residue
(original residue number in PDB)		I142 M146 W300 L333 M372 A373 Y377 A413
Binding residue
(residue number reindexed from 1)		I142 M146 W300 L333 M372 A373 Y377 A413
Annotation score1
Enzymatic activity
Enzyme Commision number 7.1.1.8: quinol--cytochrome-c reductase.
Gene Ontology
Molecular Function
GO:0008121 ubiquinol-cytochrome-c reductase activity
GO:0009055 electron transfer activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0022904 respiratory electron transport chain
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7qho, PDBe:7qho, PDBj:7qho
PDBsum7qho
PubMed35087070
UniProtQ79VE9|QCRB_CORGL Cytochrome bc1 complex cytochrome b subunit (Gene Name=qcrB)

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