Structure of PDB 6vzr Chain B Binding Site BS05

Receptor Information
>6vzr Chain B (length=402) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKRLVINLSNCRYDSVRRAAQQYGLREAGDNDDWTLYWTDYSVSLERVME
MKSYQKINHFPGMSEICRKDLLARNMSRMLKLFPKDFHFFPRTWCLPADW
GDLQTYSRTRKNKTYICKPDSGARGRGIFITRSVKEIKPGEDMICQLYIS
KPFIIDGFKFDLRVYVLVTSCDPLRVFVYNEGLARFATTSYSHPNLDNLD
EICMHLTNYSINKHSSNFVQDAFSGSKRKLSTFNSYMKTHGYDVEQIWRG
IEDVIIKTLISAHPVIKHNYHTCFPSHTLNSACFEILGFDILLDRKLKPW
LLEVNISPSFSTDSKLDKEVKDSLLYDALVLINLGNCDKKKVLEEERQRG
RFLQQNREIRLEEVKGFQAMRLQKTEEYEKKNCGGFRLIYPGLNLEKYDK
FF
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6vzr Chain B Residue 607 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6vzr Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		E359 N361
Binding residue
(residue number reindexed from 1)		E303 N305
Annotation score1
Enzymatic activity
Enzyme Commision number 6.3.2.-
Gene Ontology
Biological Process
GO:0036211 protein modification process

View graph for
Biological Process
External links
PDB RCSB:6vzr, PDBe:6vzr, PDBj:6vzr
PDBsum6vzr
PubMed32747782
UniProtA4Q9E8|TTLL6_MOUSE Tubulin polyglutamylase TTLL6 (Gene Name=Ttll6)

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