Structure of PDB 6om4 Chain B Binding Site BS05

Receptor Information

>6om4 Chain B (length=344) Species: 562 (Escherichia coli)

MDYILGRYVKIARYGSGGLVGGGGKEQYVENLVLWENIIKTAYCFITPSS
YTAALETANIPEKDFSNCFRFLKENFFIIPSEYNNNNRYSRNFLHYQSYG
ANPVLVQDKLKNAKVVILGCGGIGNHVSVILATSGIGEIILIDNDQIENT
NLTRQVLFSEDDVGKNKTEVIKRELLKRNSEISVSEIALNINDYTDLHKV
PEADIWVVSADHPFNLINWVNKYCVRANQPYINAGYVNDIAVFGPLYVPG
KTGCYECQKVVADLYGAEKENIDHKIKLINSRFKPATFAPVNNVAAALCA
ADVIKFIGKYSEPLSLNKRIGIWSDEIKIHSQNMGRSPVCSVCG

Ligand information

• Ligand ID: POP
• InChI: InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-2
• InChIKey: XPPKVPWEQAFLFU-UHFFFAOYSA-L
• SMILES:
  OpenEye OEToolkits 1.5.0: O[P@@](=O)([O-])O[P@@](=O)(O)[O-]
  CACTVS 3.341: O[P]([O-])(=O)O[P](O)([O-])=O
  ACDLabs 10.04: [O-]P(=O)(O)OP([O-])(=O)O
  OpenEye OEToolkits 1.5.0: OP(=O)([O-])OP(=O)(O)[O-]
• Formula: H2 O7 P2
• Name: PYROPHOSPHATE 2-
• PDB chain: 6om4 Chain B Residue 404

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6om4 Biosynthesis of the RiPP trojan horse nucleotide antibiotic microcin C is directed by theN-formyl of the peptide precursor.
• Resolution: 1.7 Å
• Binding residue (original residue number in PDB): N154 R157 Q158 K170
• Binding residue (residue number reindexed from 1): N151 R154 Q155 K167
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0004792 thiosulfate sulfurtransferase activity
• GO:0005515 protein binding
• GO:0005524 ATP binding
• GO:0008641 ubiquitin-like modifier activating enzyme activity
• GO:0016779 nucleotidyltransferase activity
• GO:0046872 metal ion binding

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:6om4, PDBe:6om4, PDBj:6om4
• PDBsum: 6om4
• PubMed: 30881667
• UniProt: Q47506