Structure of PDB 5t9t Chain B Binding Site BS05

Receptor Information
>5t9t Chain B (length=526) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPES
GDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNAP
LFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEVT
EKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRIQ
VTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYAF
HNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHC
SIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGD
VYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPP
LSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDL
GSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLT
LQARDHGSPTLSANVSMRVLVGDRND
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5t9t Chain B Residue 605 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5t9t gamma-Protocadherin structural diversity and functional implications.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		E114 E173 D204 I205 D207 D240
Binding residue
(residue number reindexed from 1)		E113 E172 D203 I204 D206 D239
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5t9t, PDBe:5t9t, PDBj:5t9t
PDBsum5t9t
PubMed27782885
UniProtQ8K486

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