Structure of PDB 5hrl Chain B Binding Site BS05

Receptor Information

>5hrl Chain B (length=176) Species: 10497 (African swine fever virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GGMLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLN
DVDLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQ
LDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTL
VPLKITTEKELIKELGFTYRIPKKRL

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

5hrl Chain B Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5hrl The crystal structure of Se-AsfvPolX(L52/163M mutant) in complex with 1nt-gap DNA1
Resolution	2.4 Å
Binding residue (original residue number in PDB)	D49 D51 D100
Binding residue (residue number reindexed from 1)	D51 D53 D102
Annotation score	1

Enzymatic activity

Enzyme Commision number

2.7.7.7: DNA-directed DNA polymerase.

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003887	DNA-directed DNA polymerase activity
GO:0016779	nucleotidyltransferase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006259	DNA metabolic process
GO:0006281	DNA repair
GO:0006303	double-strand break repair via nonhomologous end joining
GO:0071897	DNA biosynthetic process

	Cellular Component
GO:0044423	virion component

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Cellular Component

External links

PDB	RCSB:5hrl, PDBe:5hrl, PDBj:5hrl
PDBsum	5hrl
PubMed
UniProt	P42494\|DPOLX_ASFB7 Repair DNA polymerase X (Gene Name=Ba71V-97)

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