Structure of PDB 5axh Chain B Binding Site BS05

Receptor Information
>5axh Chain B (length=587) Species: 340099 (Thermoanaerobacter pseudethanolicus ATCC 33223) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NIFSFKDDNNIVALTKGKLISDVYTDKARYYPSDKVTVKIELNNELQEDF
RGTIYIFYKHLESIVGKAKIQVNIKSGQKKQLNIFWEAPKDDFKGYLVEV
YAVKGNKAIDNKNTAVDVSSDWSKFPRYGYIANFPEQSKEKSALIIEDLN
KYHLNGLLFYDWQYKHNKPLAGTVENPDPKWKDIANRDIYGQTVKDYIEL
AHSKNIMVANYNLMYGGYFDYVKDGAKPEWGLYKDPNHEEQDNHPLPHTW
ATDRLYLFNPANKDWQNYIFNAEKDAFRVYNFDVWHVGTLGPRGMVYDYN
GNPVELSFTYADFLNNAKNALGKRIVCNTVNEYGLINVASGADVDFLYVE
IWPPARAHYNFLKQTVDNGYNYSDGKKATVVAAYMNYGIADRSAEFNKHS
VRLTDAAIFAAGGDHIELGDTGMLSKEYFPSANLKMSESLVKAMRNYYDF
LTAYENLLRDGLKESDNKIEIPGIEISNNGSARTVWTYAKQKDGYDVIHM
INLLGIEVSNWRDDLGNYSAPPIIKDFKVKYYLENDNIKNVYLASPDIND
GKVMKLQFKKKEDSKGKYLEISVPELQYWDMIFIKKL
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain5axh Chain D Residue 5 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5axh Crystal structure of thermophilic dextranase from Thermoanaerobacter pseudethanolicus
Resolution2.2 Å
Binding residue
(original residue number in PDB)		H268 W274
Binding residue
(residue number reindexed from 1)		H244 W250
Annotation score4
Enzymatic activity
Enzyme Commision number 3.2.1.11: dextranase.
Gene Ontology
Molecular Function
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0033904 dextranase activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:5axh, PDBe:5axh, PDBj:5axh
PDBsum5axh
PubMed26494689
UniProtB0KBZ7

[Back to BioLiP]