Structure of PDB 3wv6 Chain B Binding Site BS05

Receptor Information
>3wv6 Chain B (length=284) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSQAPYLSPAVPFSGTIQGGLQDGLQITVNGTVLSSSGTRFAVNFQTGFS
GNDIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFL
VQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQHMYPHP
AYPMPFITTILGGLYPSKSILLSGTVLPSAQSFHINLCSGNHIAFHLNPR
FDENAVVRNTQIDNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAV
DGQHLFEYYHRLRNLPTINRLEVGGDIQLTHVQT
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3wv6 Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3wv6 X-ray structure of a protease-resistant mutant form of human galectin-9 having two carbohydrate recognition domains with a metal-binding site
Resolution1.95 Å
Binding residue
(original residue number in PDB)		D100 C102 H188 H320
Binding residue
(residue number reindexed from 1)		D96 C98 H149 H281
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:3wv6, PDBe:3wv6, PDBj:3wv6
PDBsum3wv6
PubMed28687490
UniProtO00182|LEG9_HUMAN Galectin-9 (Gene Name=LGALS9)

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