Structure of PDB 3j16 Chain B Binding Site BS05

Receptor Information
>3j16 Chain B (length=608) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSDKNSRIAIVSADKCKPKKCRQECKRSCPVVKTGKLCIEVTPTSKIAFI
SEILCIGCGICVKKCPFDAIQIINLPTNLEAHVTHRYSANSFKLHRLPTP
RPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFDDPPEWQEIIKYFRGS
ELQNYFTKMLEDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRMEKSPE
DVKRYIKILQLENVLKRDIEKLSGGELQRFAIGMSCVQEADVYMFDEPSS
YLDVKQRLNAAQIIRSLLAPTKYVICVEHDLSVLDYLSDFVCIIYGVPSV
YGVVTLPASVREGINIFLDGHIPAENLRFRTEALQFRIADATEDLQNDSA
SRAFSYPSLKKTQGDFVLNVEEGEFSDSEILVMMGENGTGKTTLIKLLAG
ALKPDEGQDIPKLNVSMKPQKIAPKFPGTVRQLFFKKIRGQFLNPQFQTD
VVKPLRIDDIIDQEVQHLSGGELQRVAIVLALGIPADIYLIDEPSAYLDS
EQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIVFEGIPSKNAH
ARAPESLLTGCNRFLKNLNVTFRRDPNSFRPRINKLDSQMDKEQKSSGNY
FFLDNTGI
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain3j16 Chain B Residue 703 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3j16 Structural basis of highly conserved ribosome recycling in eukaryotes and archaea.
Resolution7.2 Å
Binding residue
(original residue number in PDB)		C29 V31 C38 I39 I50 C55 I56 C58 G59 I60 C61
Binding residue
(residue number reindexed from 1)		C29 V31 C38 I39 I50 C55 I56 C58 G59 I60 C61
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003743 translation initiation factor activity
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0043024 ribosomal small subunit binding
Biological Process
GO:0000054 ribosomal subunit export from nucleus
GO:0006364 rRNA processing
GO:0006412 translation
GO:0006413 translational initiation
GO:0006415 translational termination
GO:0032790 ribosome disassembly
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
GO:0045727 positive regulation of translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005852 eukaryotic translation initiation factor 3 complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3j16, PDBe:3j16, PDBj:3j16
PDBsum3j16
PubMed22358840
UniProtQ03195|RLI1_YEAST Translation initiation factor RLI1 (Gene Name=RLI1)

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