Structure of PDB 2w6d Chain B Binding Site BS05

Receptor Information
>2w6d Chain B (length=680) Species: 63737 (Nostoc punctiforme PCC 73102) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VNQVATDRFIQDLERVAQVRSEMSVCLNKLAETINKAELAGDSSSGKLSL
ERDIEDITIASKNLQQGVFRLLVLGDMKRGKSTFLNALIGENLLPSTAVL
TVLRYGPEKKVTIHFNDGKSPQQLDFQNFKYKYTIDPAEAKKLEQEKKQA
FPDVDYAVVEYPLTLLQKGIEIVDSPGLNDTEARNELSLGYVNNCHAILF
VMRASQPCTLGERRYLENYIKGRGLTVFFLVNAWDQVRESLIDPDDVEEL
QASENRLRQVFNANLAEYCTVEGQNIYDERVFELSSIQALRRRLKNPQAD
LDGTGFPKFMDSLNTFLTRERAIAELRQVRTLARLACNHTREAVARRIPL
LEQDVNELKKRIDSVEPEFNKLTGIRDEFQKEIINTRDTQARTISESFRS
YVLNLGNTFENDFLRYQPELNLFDFLSSGKREAFNAALQKAFEQYITDKS
AAWTLTAEKDINAAFKELSRSASQYGASYNQITDQITEKLTGKDVEDNSP
GWAKWAMGLLSLSKGNLAGFALAGAGFDWKNILLNYFTVIGIGGIITAVT
GILLGPIGFALLGLGVGFLQADQARRELVKTAKKELVKHLPQVAHEQSQV
VYNAVKECFDSYEREVSKRINDDIVSRKSELDNLVKQKQTREINRESEFN
RLKNLQEDVIAQLQKIEAAYSNLLAYYSHH
Ligand information
Ligand IDCPL
InChIInChI=1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1
InChIKeyJLPULHDHAOZNQI-ZTIMHPMXSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(OCC(OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COP([O-])(=O)OCC[N+](C)(C)C)CCCCCCCCCCCCCCC
OpenEye OEToolkits 1.5.0CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCC=CCCCCC
CACTVS 3.341CCCCCCCCCCCCCCCC(=O)OC[CH](CO[P]([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCC=CCCCCC
CACTVS 3.341CCCCCCCCCCCCCCCC(=O)OC[C@H](CO[P]([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C/C=C\CCCCC
OpenEye OEToolkits 1.5.0CCCCCCCCCCCCCCCC(=O)OC[C@H](CO[P@@](=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC
FormulaC42 H80 N O8 P
Name1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;
PALMITOYL-LINOLEOYL PHOSPHATIDYLCHOLINE
ChEMBL
DrugBankDB02306
ZINC
PDB chain2w6d Chain B Residue 1698 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2w6d Structure of a Bacterial Dynamin-Like Protein Lipid Tube Provides a Mechanism for Assembly and Membrane Curving.
Resolution9.0 Å
Binding residue
(original residue number in PDB)		K436 G580
Binding residue
(residue number reindexed from 1)		K430 G565
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.5: dynamin GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0008289 lipid binding
GO:0016787 hydrolase activity
GO:0042802 identical protein binding
Biological Process
GO:0008053 mitochondrial fusion
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2w6d, PDBe:2w6d, PDBj:2w6d
PDBsum2w6d
PubMed20064379
UniProtB2IZD3|BDLP_NOSP7 Bacterial dynamin-like protein (Gene Name=Npun_R6513)

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