Structure of PDB 1xhv Chain B Binding Site BS05
Receptor Information
>1xhv Chain B (length=252) Species:
727
(Haemophilus influenzae) [
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SFIKPIYQDINSILIGQKVKRPKSGHAAGEPFEKLVYKFLKENLSDLTFK
QYEYLNDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLF
EEKQNDTADILLVKDQFYELLDVKTRNISKSAQAPNIISAYKLAQTCAKM
IDNKEFDLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAA
MQIQFHVRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKK
YI
Ligand information
Ligand ID
MN
InChI
InChI=1S/Mn/q+2
InChIKey
WAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mn+2]
CACTVS 3.341
[Mn++]
Formula
Mn
Name
MANGANESE (II) ION
ChEMBL
DrugBank
DB06757
ZINC
PDB chain
1xhv Chain B Residue 1101 [
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Receptor-Ligand Complex Structure
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PDB
1xhv
Mechanistic Insights from the Structures of HincII Bound to Cognate DNA Cleaved from Addition of Mg(2+) and Mn(2+)
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
E38 D114 V128
Binding residue
(residue number reindexed from 1)
E33 D109 V123
Annotation score
4
Enzymatic activity
Enzyme Commision number
3.1.21.4
: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0004519
endonuclease activity
GO:0009036
type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307
DNA restriction-modification system
View graph for
Molecular Function
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Biological Process
External links
PDB
RCSB:1xhv
,
PDBe:1xhv
,
PDBj:1xhv
PDBsum
1xhv
PubMed
15476804
UniProt
P17743
|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)
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