Structure of PDB 8v1t Chain A Binding Site BS05

Receptor Information
>8v1t Chain A (length=1064) Species: 10306 (Human alphaherpesvirus 1 strain KOS) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPTQRHTYYSECDEFRFIAPRVLDEDAPPEKRAGVHDGHLKRAPKVYCGG
DERDVLRVGSGGFWPRRSRLWGGVDHAPAGFNPTVTVFHVYDILENVEHA
YGMRAAQFHARFMDAITPTGTVITLLGLTPEGHRVAVHVYGTRQYFYMNK
EEVDRHLQCRASADHFEAEVVERTDVYYYETRPALFYRVYVRSGRVLSYL
CDNFCPAIKKYEGGVDATTRFILDNPGFVTFGWYRLKPGRNNTLAQPRAP
MAFGTSSDVEFNCTADNLAIEGGMSDLPAYKLMCFDIECKAGGEDELAFP
VAGHPEDLVIQISCLLYDLSTTALEHVLLFSLGSCDLPESHLNELAARGL
PTPVVLEFDSEFEMLLAFMTLVKQYGPEFVTGYNIINFDWPFLLAKLTDI
YKVPLDGYGRMNGRGVFRVWDIGQSHFQKRSKIKVNGMVNIDMYGIITDK
IKLSSYKLNAVAEAVLKDKKKDLSYRDIPAYYATGPAQRGVIGEYCIQDS
LLVGQLFFKFLPHLELSAVARLAGINITRTIYDGQQIRVFTCLLRLADQK
GFILPDTQGRFRGRHVGYQGARVLDPTSGFHVNPVVVFDFASLYPSIIQA
HNLCFSTLSLRADAVAHLEAGKDYLEIEVGGRRLFFVKAHVRESLLSILL
RDWLAMRKQIRSRIPQSSPEEAVLLDKQQAAIKVVCNSVYGFTGVQHGLL
PCLHVAATVTTIGREMLLATREYVHARWAAFEQLLADFPEAADMRAPGPY
SMRIIYGDTDSIFVLCRGLTAAGLTAMGDKMASHISRALFLPPIKLECEK
TFTKLLLIAKKKYIGVIYGGKMLIKGVDLVRKNNCAFINRTSRALVDLLF
YDDTVSGAAAALAERPAEEWLARPLPEGLQAFGAVLVDAHRRITDPERDI
QDFVLTAELSRHPRAYTNKRLAHLTVYYKLMARRAQVPSIKDRIPYVIVA
QTREVEETVARLARKLLVSELAEDPAYAIAHGVALNTDYYFSHLLGAACV
TFKALFGNNAKITESLLKRFIPEVWHPPDDVAARLRAAGFGAVGAGATAE
ETRRMLHRAFDTLA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8v1t Chain A Residue 1303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8v1t Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		D368 D581
Binding residue
(residue number reindexed from 1)		D286 D499
Annotation score1
External links