Structure of PDB 8gh6 Chain A Binding Site BS05

Receptor Information
>8gh6 Chain A (length=898) Species: 7091 (Bombyx mori) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GWTCQFCERTFSTNRGLGVHKRRAHPVETNTDAAPMMVKRRWHGEEIDLL
ARTEARLLAERGQCSGGDLFGALPGFGRTLEAIKGQRRREPYRALVQAHL
ARFGSTSRQKRRAEYARVQELYKKCRSRAAAEVIDGACGGVGHSLEEMET
YWRPILERVSDAPGPTPEALHALGRTQLWKPISVEEIKASRFDWRTSPGP
DGIRSGQWRAVPVHLKAEMFNAWMARGEIPEILRQCRTVFVPKVERPGGP
GEYRPISIASIPLRHFHSILARRLLACCPPDARQRGFICADGTLENSAVL
DAVLGDSRKKLRECHVAVLDFAKAFDTVSHEALVELLRLRGMPEQFCGYI
AHLYDTASTTLAVNNEMSSPVKVGRGVRQGDPLSPILFNVVMDLILASLP
ERVGYRLEMELVSALAYADDLVLLAGSKVGMQESISAVDCVGRQMGLRLN
CRKSAVLSMIPDGHRKKHHYLTERTFNIGGKPLRQVSCVERWRYLGVDFE
ASGCVTLEHSISSALNNISRAPLKPQQRLEILRAHLIPRFQHGFVLGNIS
DDRLRMLDVQIRKAVGQWLRLPADVPKAYYHAAVQDGGLAIPSVRATIPD
LIVRRFGGLDSSPWSVARAAAKSDKIRKKLRWAWKQLRRFSRVDSTTQRP
SVRLFWREHLHASVDGRELRESTRTPTSTKWIRERCAQITGRDFVQFVHT
HINALPSRIRGSRGRRGGGESSLTCRAGCKVRETTAHILQQCHRTHGGRI
LRHNKIVSFVAKAMEENKWTVELEPRLRTSVGLRKPDIIASRDGVGVIVD
VQVVSGQRSLDELHREKRNKYGNHGELVELVAGRLGLPKAECVRATSCTI
SWRGVWSLTSYKELRSIIGLREPTLQIVPILALRGSHMNWTRFNQMTS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8gh6 Chain A Residue 1201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8gh6 Structure of the R2 non-LTR retrotransposon initiating target-primed reverse transcription.
Resolution3.08 Å
Binding residue
(original residue number in PDB)		C114 C117 H130 H135
Binding residue
(residue number reindexed from 1)		C4 C7 H20 H25
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003964 RNA-directed DNA polymerase activity
Biological Process
GO:0006278 RNA-templated DNA biosynthetic process
GO:0071897 DNA biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8gh6, PDBe:8gh6, PDBj:8gh6
PDBsum8gh6
PubMed37023171
UniProtV9H052

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