Structure of PDB 8fs8 Chain A Binding Site BS05

Receptor Information
>8fs8 Chain A (length=426) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GEQWYEKFKPNCLEQVAIHKRKLKDVQEALDAMFLPNAKHRILLLSGPSG
CSKSTVIKELSKILVPKYRQNSHKVTEFRGDCIVNDLPQMESFSEFLKGA
RYLVMSNLSLILIEDLPNVFHIDTRRRFQQLILQWLYSSEPLLPPLVICI
TECEIPENDNNYRKFGIDYTFSAETIMNKEILMHPRLKRIKFNPINSTLL
KKHLKFICVQNMKMLKEKNKWNKRQEVIDYIAQETGDIRSAITTLQFWAT
SSGSLPISTRESTISYFHAIGKVIHGSHSTNNDNEMINNLFENSNNLLSK
EDFKLGILENYNTFNKGEFSISDASSIVDCLSECDNMNGLPESNEYGLRE
VRKTFRNISKQGHNHGTVYFPREWKVRKLQNSFKVQAEDWLNVSLYKYNA
VHSFRNITLEFGYYAPLIRKCQSYKK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8fs8 Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8fs8 Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology.
Resolution3.04 Å
Binding residue
(original residue number in PDB)		S116 E187
Binding residue
(residue number reindexed from 1)		S54 E114
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003689 DNA clamp loader activity
Biological Process
GO:0000077 DNA damage checkpoint signaling
GO:0006281 DNA repair
Cellular Component
GO:0005634 nucleus
GO:0031389 Rad17 RFC-like complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fs8, PDBe:8fs8, PDBj:8fs8
PDBsum8fs8
PubMed37205533
UniProtP32641|RAD24_YEAST Checkpoint protein RAD24 (Gene Name=RAD24)

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