Structure of PDB 8a0c Chain A Binding Site BS05

Receptor Information
>8a0c Chain A (length=1116) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VDKTWLFGSYAWQGNPKALFLYMLVNCKETHECWWVADNEESMKSIKKST
GLKNITFTDSEKAKELFPHADVYVTENFRESYPVYMNENIKVFNTWHGVG
LKHIELALGMNSVLAESIVRKYVRNYDIYKNNVLFLTTSQAMEDHFLEDM
AISKELIIRGKYPRNAVYGPNGIHTYDINTLLPKNKSQYSQTILFCPTYR
IGAIQGVLNSLLPDFAKLEEVCRHKNQLFIVKVHPFMKKDNYFAEMSEKY
KDSEYILFWNDDYDIYEAFNSIDLAIIDYSSIFYDLLDAGVEKFIRYVPD
LDEYQNDLELIGDYADLTEGRIVKSFQQLLNCLDNANIKIISTKRKQYLM
DYFFGFKKENKSMESLIADVDNCQLQPKSLKELHTFDIFDTLIRRSTLRP
FSIFDYVRDKAKASGIKFPLALTENWINVRNRAEHDVRDIMRKTTFERQS
DKIEITLDDIYTRLQKNLLLTDEQTDFLKQAEIEAEIAHVEPIQKRINYL
FSLKAKGHDVAMASDMYLPEDVIYKMLDRADTRLREIPLYLSSTIGYQKS
TGKLYQHIFFDLDYQYSRWTHYGDNKHADGSVPRRLGIQTAVHDIDDFIP
FENAMVNAMDNYNRYPAYQLATKMHRYRTQLVQENGFGNTLFETKYYNYA
YVGASFVPYINWAIKDAIKRGYETIYFISRDGHFLKQIADKIIEIRGYNV
KTKYIYGSRKAWRLPSFITKVDDETFWQFGNFVGMDSFEDLVKASYLSES
ELLSLFPEFESLRHAKHLRGEIAENIRKIFKNSPAYHEKVLAIAAEKRKM
VRQYIQQEINPKEKFAFVEFWGRGYTQDTFGRLLNDAFGKEVKNPFYYVR
SFTDDMGTSVRHNFILAPQNFSFFEPIFAQTPYDSIPDYYEEKGRIEPII
NHRDRSVSDLISEGLLKFTEDYLALNTQDEDYFDAALSQFNYQYQLNTPN
DQFICNVFSELKDNISSFGVEKPYAPALTLKQLESITSKQELDKLTQSIP
ISLSKSDVKVIDYYNKIQKNYNLPAYNSTPMRKAYAVNPLEQYVWSTQVP
FRVLSLKQNSFYLDVSFAETTKRKDIFLKELNEIDVIAVDWLKGGVPRLL
TEHGYITAHKDWVKKS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8a0c Chain A Residue 1209 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8a0c A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		D386 F388 D573
Binding residue
(residue number reindexed from 1)		D387 F389 D574
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0046872 metal ion binding
GO:0047355 CDP-glycerol glycerophosphotransferase activity
Biological Process
GO:0019350 teichoic acid biosynthetic process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8a0c, PDBe:8a0c, PDBj:8a0c
PDBsum8a0c
PubMed37277468
UniProtQ2ERG0

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