Structure of PDB 7y80 Chain A Binding Site BS05

Receptor Information
>7y80 Chain A (length=1218) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAGK
SFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSFL
RKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFSN
FDLDHDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGTYTGRIT
LRNEHAKKLLLASLGFVDKLCGALCRIEVIDHNDELRKQAEVIVEAFKQN
DKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHHLWDIKVQGT
ALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETTEYYSSDLFIPVT
PPEGIETKEWIIVGRLKAATPFYFGVQQPSDSIPGKEEHTSFNILLDKEN
RYRIPRSALRGALRRDLRTAFGSGCNVSLGGQILCNCKVCIEMRRITLKD
SVSDFSEPPEIRYRIAKNPGTATVEDGSLFDIEVGPEGLTFPFVLRYRGH
KFPEQLSSVIRYWEENDGKNGMAWLGGLDSTGKGRFALKDIKIFEWDLNQ
KINEYIKERGMRGKEKELLEMGESSLPDGLIPYKFFEERECLFPYKENLK
PQWSEVQYTIEVGSPLLTADTISALTEPGNRDAIAYKKRVYNDGNNAIEP
EPRFAVKSETHRGIFRTAVGRRTGDLGKEDHEDCTCDMCIIFGNEHESSK
IRFEDLELINGNEFEKLEKHIDHVAIDRFTGGALDKAKFDTYPLAGSPKK
PLKLKGRFWIKKGFSGDHKLLITTALSDIRDGLYPLGSKGGVGYGWVAGI
SIDDNVINNDYVHPGHQSPKQDHKNKNIYYPHYFLDSGSKVYREKDIITH
EEFTEELLSGKINCKLETLTPLIIPDTSDENGLKLQGNKPGHKNYKFFNI
NGELMIPGSELRGMLRTHFEALTKSCFAIFGEDSTLSASKTLGGKLDKAL
HPCTGLSDGLCPGCHLFGTTDYKGRVKFGFAKYENGPEWLITRGNNPERS
LTLGVLESPRPAFSIPDDESEIPGRKFYLHHNGWRIIRQKQLEIRETVQP
ERNVTTEVMDKGNVFSFDVRFENLREWELGLLLQSLDPGKNIAHKLGKGK
PYGFGSVKIKIDSLHTFKIKRVPQSDIREYINKGYQKLIEWSGLPQWHVI
PHIDKLYKLLWVPFLSKLEPDVRYPVLNEESKGYIEGSDYTYKKLGDKDN
LPYKTRVKGLTTPWSPWN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7y80 Chain A Residue 1804 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7y80 Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase
Resolution2.71 Å
Binding residue
(original residue number in PDB)		C1018 C1406 C1414 C1417
Binding residue
(residue number reindexed from 1)		C926 C953 C961 C964
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7y80, PDBe:7y80, PDBj:7y80
PDBsum7y80
PubMed36477448
UniProtA0A0B0EGF3

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