Structure of PDB 7xa9 Chain A Binding Site BS05

Receptor Information
>7xa9 Chain A (length=702) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HIESLDYEINENDLFKHDWRSRSKAQVFQYIFLKWTLACLVGLFTGLIAT
LINLAVENIAGYKLLAVGYYIAQDRFWTGLMVFTGANLGLTLVATVLVVY
FAPTAAGPGIPEIKAYLNGIDTPNMFGFTTMMVKIVGSIGAVAAGLDLGK
EGPLVHIGSCIASLLGQGGPDNHRIKWRWLRYFNNDRDRRDLITCGSASG
VCAAFRSPVGGVLFALEEVATWWRSALLWRTFFSTAVVVVVLRAFIEICN
SGKCGLFGSGGLIMFDVSHVEVRYHAADIIPVTLIGVFGGILGSLYNHLL
HKVLRLYNLINQKGKIHKVLLSLGVSLFTSVCLFGLPFLAECKPCDPSID
EICPTNGRSGNFKQFNCPNGYYNDLSTLLLTTNDDAVRNIFSSNTPNEFG
MVSLWIFFGLYCILGLITFGIATPSGLFLPIILMGSAYGRMLGTAMGSYT
NIDQGLYAVLGAASLMAGSMRMTVSLCVIFLELTNNLLLLPITMFVLLIA
KTVGDSFNLSIYEIILHLKGLPFLEANPEPWMRNLTVGELNDAKPPVVTL
NGVEKVANIVDVLRNTTHNAFPVLDTELHGLILRAHLVKVLKKRWFLNEK
RRTEEWEVREKFTPVELAEREDNFDDVAITSSEMQLYVDLHPLTNTTPYT
VVQSMSVAKALVLFRSVGLRHLLVVPKSPVIGILTRQDLRAYNILQAFPH
LD
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7xa9 Chain A Residue 905 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7xa9 Cryo-EM structure of the plant nitrate transporter AtCLCa reveals characteristics of the anion-binding site and the ATP-binding pocket.
Resolution2.84 Å
Binding residue
(original residue number in PDB)		H53 E55
Binding residue
(residue number reindexed from 1)		H1 E3
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005247 voltage-gated chloride channel activity
GO:0005254 chloride channel activity
GO:0005515 protein binding
GO:0015112 nitrate transmembrane transporter activity
Biological Process
GO:0006821 chloride transport
GO:0010167 response to nitrate
GO:0015706 nitrate transmembrane transport
GO:0034220 monoatomic ion transmembrane transport
GO:0055085 transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0034707 chloride channel complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xa9, PDBe:7xa9, PDBj:7xa9
PDBsum7xa9
PubMed36581207
UniProtP92941|CLCA_ARATH Chloride channel protein CLC-a (Gene Name=CLC-A)

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