Structure of PDB 7o6d Chain A Binding Site BS05

Receptor Information
>7o6d Chain A (length=173) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPSRVRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALNNFSR
YFLHQSREETEHAEKLMRLQNQRGGRIRLQDIKKPEQDDWESGLHAMECA
LLLEKNVNQSLLELHALASDKGDPHLCDFLETYYLNEQVKSIKELGDHVH
NLVKMGAPDAGLAEYLFDTHTLG
Ligand information
Ligand IDFE2
InChIInChI=1S/Fe/q+2
InChIKeyCWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Fe+2]
CACTVS 3.341[Fe++]
FormulaFe
NameFE (II) ION
ChEMBL
DrugBankDB14510
ZINC
PDB chain7o6d Chain A Residue 207 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7o6d Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
Resolution1.47 Å
Binding residue
(original residue number in PDB)		E140 S144
Binding residue
(residue number reindexed from 1)		E137 S141
Annotation score5
Enzymatic activity
Enzyme Commision number 1.16.3.1: ferroxidase.
Gene Ontology
Molecular Function
GO:0008199 ferric iron binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis

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Molecular Function
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Biological Process
External links
PDB RCSB:7o6d, PDBe:7o6d, PDBj:7o6d
PDBsum7o6d
PubMed34343376
UniProtQ8N4E7|FTMT_HUMAN Ferritin, mitochondrial (Gene Name=FTMT)

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