Structure of PDB 7c68 Chain A Binding Site BS05

Receptor Information

>7c68 Chain A (length=417) Species: 300852 (Thermus thermophilus HB8)

QKTLEVWIMPNSPQPAEDFKALVAPFEKAHGVEVKVTVLDWGVAWTKITT
AATSGVGPDLTQLGTTWVGAISAMGVLEPVDDVLEALGGEKAYLPAVWRT
TRLEGARQATAVPWFSELRAFYYRTDALKAAGVNPAEMFASWQGFEAGLA
RLKASSFRDPETKAPLAPLCTPGKNSWDVLHNAAPWIWGAGGEIVRQAGG
RWQSALNSPESLEGLYFFLSLAQKGYVPAESLEKNTAQIEADFQAGKCAV
FASGPWMIQRAQVPEAKGGFAERTAAKNLGVAPYPAGPKGRYTFFGGSNL
ALFNFSKNKPLAKELLKYLGGPEAQVRYAQMTGMLPALRSAWSDPSFQQN
PLLRTFIQAAQFGRTYPSLAGWGGVENLAVQHLGMAWDLVAQGRLTREAL
KDLMDKASAAINQALRH

Ligand information

• Ligand ID: SO3
• InChI: InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-2
• InChIKey: LSNNMFCWUKXFEE-UHFFFAOYSA-L
• SMILES:
  CACTVS 3.341: [O-][S]([O-])=O
  OpenEye OEToolkits 1.5.0: [O-]S(=O)[O-]
  ACDLabs 10.04: [O-]S([O-])=O
• Formula: O3 S
• Name: SULFITE ION
• PDB chain: 7c68 Chain A Residue 505

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7c68 Conformational Trapping of a beta-Glucosides-Binding Protein Unveils the Selective Two-Step Ligand-Binding Mechanism of ABC Importers.
• Resolution: 2.05 Å
• Binding residue (original residue number in PDB): E230 K234 D242 K247
• Binding residue (residue number reindexed from 1): E230 K234 D242 K247
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:1901982 maltose binding

Biological Process

• GO:0015768 maltose transport
• GO:0042956 maltodextrin transmembrane transport

Cellular Component

• GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

External links

• PDB: RCSB:7c68, PDBe:7c68, PDBj:7c68
• PDBsum: 7c68
• PubMed: 32866452
• UniProt: Q53W80