Structure of PDB 6zm2 Chain A Binding Site BS05

Receptor Information
>6zm2 Chain A (length=627) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TIQEVRKSLPVYAYRDAFLDAVKEYQVLILVGETGSGKTTQIPQYLHEAG
YTKGNRKIACTQPRRVAAMSVAARVADEMGVRLGHEVGYSIRFEDCTSEK
TILKYMTDGMLLREMVTSPDLADYSCIMIDEAHERTVHTDILLALIKDLT
RARPELRLIISSATLNAEKFSAYFDDAPIFNVPGRVHPVEVYYTSAPESN
YLEAALVTVFQIHATQPEGDILVFLTGQEEIERACERVEEIRRKLGPEII
ALPIYSNMPSEMQAKIFEPTPPGARKVVFSTNIAETSLTIDGIVYVIDSG
YVKENTFSPVGTTGQSTLAVVPCSRAAANQRMGRAGRVKPGKCFRLYTKY
AYLSEMDESPTPEIQRTSLSSVVLQLKALGIDDLLGFDFLDPPPTELLIK
SLNMLYALGALNSAGQLTRVGRQMGEFPTEPMLAKALIAATQEGCVSEVL
TIVSMLGEVGTLFFRPKDKKVHADSARARFTVRDGGDHLTLLNIYNQWVE
AEYSPIWARENFLAQRSLTRARDVRDQLAKLCDRILDGSEASCGGVNNPT
PILRALTAAFFLNAARLNRAGDGYRTLKNNITVYVHPSSVVRGMDPPPKV
IIYHELVVTSKEYVRSVIPVEPRWLSE
Ligand information
Ligand IDPOL
InChIInChI=1S/C3H8O/c1-2-3-4/h4H,2-3H2,1H3
InChIKeyBDERNNFJNOPAEC-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		CCCO
ACDLabs 10.04OCCC
FormulaC3 H8 O
NameN-PROPANOL;
1-PROPONOL
ChEMBLCHEMBL14687
DrugBankDB03175
ZINCZINC000000895969
PDB chain6zm2 Chain A Residue 1118 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zm2 The structure of Prp2 bound to RNA and ADP-BeF 3 - reveals structural features important for RNA unwinding by DEAH-box ATPases.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		L307 K311 Y339
Binding residue
(residue number reindexed from 1)		L19 K23 Y51
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:6zm2, PDBe:6zm2, PDBj:6zm2
PDBsum6zm2
PubMed33825710
UniProtG0SEG4

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