Structure of PDB 6z1s Chain A Binding Site BS05

Receptor Information

>6z1s Chain A (length=381) Species: 573729 (Thermothelomyces thermophilus ATCC 42464) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GDDLTEPKELTDLFEKAKKAVIDRLHEDEKALRARPRCTADKLIFRREYG
SLSKDERLAYVNAVKCLQSKPPRTPASVAPGARSRFDDFVVVHIQQTLDI
HYSGIFQAWHRWFVYQYEKALRDECGYTGYQPYWDWPKYASAPQDSPLFN
GDPYSLGGNGEYVPHDGPVIVPPEGNISLPAGVGGGFVRTGPFANMTVNL
GPVGGLADTAPGPQGGLGYNPRGLKRDLGGAMNTRYANYTTVLRLLTQPD
VDAFRTVSEGVPYTVEIGPHNGIHYTIGGDPGGDLFTSPGDPAFWVHHAQ
MDRVWATWQALGLLPPGDPDPARRYTDLGKGDYAHRTWQNSPPSPFAELS
DVIDMGYAAPSTTIGAVMSTTEGELCYFYLE

Ligand information

Ligand ID

InChI

InChI=1S/Cu/q+2

InChIKey

JPVYNHNXODAKFH-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Cu+2]
CACTVS 3.341	[Cu++]

Formula

Name

COPPER (II) ION

PDB chain

6z1s Chain A Residue 513 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6z1s Considerations Regarding Activity Determinants of Fungal Polyphenol Oxidases Based on Mutational and Structural Studies.
Resolution	1.53 Å
Binding residue (original residue number in PDB)	H291 H295 H319
Binding residue (residue number reindexed from 1)	H270 H274 H298
Annotation score	3

Enzymatic activity

Catalytic site (original residue number in PDB)	H118 H127 H291 H295 L306 H319
Catalytic site (residue number reindexed from 1)	H101 H110 H270 H274 L285 H298
Enzyme Commision number	?

Gene Ontology

	Molecular Function
GO:0004497	monooxygenase activity
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:6z1s, PDBe:6z1s, PDBj:6z1s
PDBsum	6z1s
PubMed	33741634
UniProt	G2QLD3

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