Structure of PDB 6v0v Chain A Binding Site BS05

Receptor Information
>6v0v Chain A (length=541) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVL
LPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYD
SALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKPE
KAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHET
LTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEG
LEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHE
SVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYK
HPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVC
ELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFA
ELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKL
FRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6v0v Chain A Residue 1103 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6v0v Cutting antiparallel DNA strands in a single active site.
Resolution3.61 Å
Binding residue
(original residue number in PDB)		C727 C730 H937 H942
Binding residue
(residue number reindexed from 1)		C260 C263 H470 H475
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6v0v, PDBe:6v0v, PDBj:6v0v
PDBsum6v0v
PubMed32015552
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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