Structure of PDB 6rke Chain A Binding Site BS05

Receptor Information

>6rke Chain A (length=272) Species: 322710 (Azotobacter vinelandii DJ)

TNSIKHVISPLARQTLQDRDLTRPVAGKRPIRLLPWLQVVKIGGRVMDRG
ADAILPLVEELRKLLPEHRLLILTGAGVRARHVFSVGLDLGLPVGSLAPL
AASEAGQNGHILAAMLASEGVSYVEHPTVADQLAIHLSATRAVVGSAFPP
YHHHEFPGSRIPPHRADTGAFLLADAFGAAGLTIVENVDGIYTADPNGPD
RGQARFLPETSATDLAKSEGPLPVDRALLDVMATARHIERVQVVNGLVPG
RLTAALRGEHVGTLIRTGVRPA

Ligand information

• Ligand ID: M10
• InChI: InChI=1S/3Mo.13O/q;;;;;;;;8*-1
• InChIKey: HGNGIYFURFJYFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.370: [O-][Mo]|12([O-])([O-])O[Mo]3([O-])([O-])([O-])O|1[Mo]([O-])([O-])(=O)(O2)O3
  OpenEye OEToolkits 1.7.6: [O-][Mo]12(O[Mo]3(O1[Mo](=O)(O2)(O3)([O-])[O-])([O-])([O-])[O-])([O-])[O-]
• Formula: Mo3 O13
• Name: (mu3-oxo)-tris(mu2-oxo)-nonakisoxo-trimolybdenum (VI);
  Trimolybdate [Mo(VI)3O13]8-
• PDB chain: 6rke Chain A Residue 304

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6rke Molybdate pumping into the molybdenum storage protein via an ATP-powered piercing mechanism.
• Resolution: 1.7 Å
• Binding residue (original residue number in PDB): Q136 H140
• Binding residue (residue number reindexed from 1): Q132 H136
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0030151 molybdenum ion binding
• GO:0045735 nutrient reservoir activity
• GO:0046872 metal ion binding

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:6rke, PDBe:6rke, PDBj:6rke
• PDBsum: 6rke
• PubMed: 31811022
• UniProt: P84308|MOSA_AZOVD Molybdenum storage protein subunit alpha (Gene Name=mosA)