Structure of PDB 5ze1 Chain A Binding Site BS05

Receptor Information
>5ze1 Chain A (length=618) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALR
ARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKA
ITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSG
LASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGP
FTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKV
FEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLE
MGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQN
LVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPS
IDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKR
MNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMK
PVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTL
AHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKH
HWLYTSKYLQKFMNAHNA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5ze1 Cracking the DNA Code for V(D)J Recombination
Resolution3.0 Å
Binding residue
(original residue number in PDB)		R401 K405 S477 C478 S479 Q480 K483 R504 M974 N975 A976 R977 Q978 K989
Binding residue
(residue number reindexed from 1)		R11 K15 S87 C88 S89 Q90 K93 R114 M584 N585 A586 R587 Q588 K599
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5ze1, PDBe:5ze1, PDBj:5ze1
PDBsum5ze1
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

[Back to BioLiP]