Structure of PDB 5ys5 Chain A Binding Site BS05

Receptor Information
>5ys5 Chain A (length=457) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPTLPIPDLLTTDARNRIQLTIGAGQSTFGGKTATTWGYNGNLLGPAVKL
QRGKAVTVDIYNQLTEETTLHWHGLEVPGEVDGGPQGIIPPGGKRSVTLN
VDQPAATCWFHPHQHGKTGRQVAMGLAGLVVIEDDEILKLMLPKQWGIDD
VPVIVQDKKFSADGQIDYQLDVMTAAVGWFGDTLLTNGAIYPQHAAPRGW
LRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVSELPVLMGER
FEVLVEVNDNKPFDLVTLPVSQMKMAIAPFDKPHPVMRIQPIAISASGAL
PDTLSSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLMEGGKFDFHHANK
INGQAFDMNKPMFAAAKGQYERWVISGVGDMMLHPFHIHGTQFRILSENG
KPPAAHRAGWKDTVKVEGNVSEVLVKFNHDAPKEHAYMAHCHLLEHEDTG
MMLGFTV
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain5ys5 Chain A Residue 706 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ys5 Crystal structures of multicopper oxidase CueO G304K mutant: structural basis of the increased laccase activity
Resolution2.2 Å
Binding residue
(original residue number in PDB)		E110 H494
Binding residue
(residue number reindexed from 1)		E80 H435
Annotation score5
Enzymatic activity
Enzyme Commision number 1.16.3.4: cuproxidase.
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:5ys5, PDBe:5ys5, PDBj:5ys5
PDBsum5ys5
PubMed30250139
UniProtP36649|CUEO_ECOLI Multicopper oxidase CueO (Gene Name=cueO)

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