Structure of PDB 5yjg Chain A Binding Site BS05

Receptor Information
>5yjg Chain A (length=594) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRME
GMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAP
SNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPS
MYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSI
QDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVL
ERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDS
ITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDL
VAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVK
VGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHI
FREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPT
NDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKT
TQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5yjg Chain A Residue 725 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5yjg Structural characterizations of human periostin dimerization and cysteinylation.
Resolution2.399 Å
Binding residue
(original residue number in PDB)		A110 T112 T113 P137 S138 N139
Binding residue
(residue number reindexed from 1)		A73 T75 T76 P100 S101 N102
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5yjg, PDBe:5yjg, PDBj:5yjg
PDBsum5yjg
PubMed29754429
UniProtQ15063|POSTN_HUMAN Periostin (Gene Name=POSTN)

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