Structure of PDB 5v1t Chain A Binding Site BS05

Receptor Information
>5v1t Chain A (length=439) Species: 1307 (Streptococcus suis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRTISEDILFRLEKFGGILINKTNFERIELDETEAFFLYLVQNHGIEIAT
SFFKKEIEMGKLERALSLNIYSDNNIEDSLNNPYETLQNARKHVAKLKKH
NILSFPLELVIYPSMYCDLKCGFCFLANREDRNAKPAKDWERILRQAKDN
GVLSVSILGGEPTRYFDIDNLLIACEELKIKTTITTNAQLIKKSTVEILA
KSKYITPVLSLQTLDSKLNFELMGVRPDRQIKLAKYFNEVGKKCRINAVY
TKQSYEQIIELVDFCIENKIDRFSVANYSEVTGYTKIKKKYDLADLRRLN
EYVTDYITQREANLNFATEGCHLFTAYPELINNSIEFSEFDEMYYGCRAK
YTKMEIMSNGDILPCIAFLGVNQTKQNAFEKDLLDVWYDDPLYGGIRSFR
TKNSKCLSCGLLKICEGGCYVNLIKEKSPEYFRDSVCQL
Ligand information
Ligand IDMET
InChIInChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChIKeyFFEARJCKVFRZRR-BYPYZUCNSA-N
SMILES
SoftwareSMILES
CACTVS 3.341CSCC[CH](N)C(O)=O
OpenEye OEToolkits 1.5.0CSCCC(C(=O)O)N
CACTVS 3.341CSCC[C@H](N)C(O)=O
OpenEye OEToolkits 1.5.0CSCC[C@@H](C(=O)O)N
ACDLabs 10.04O=C(O)C(N)CCSC
FormulaC5 H11 N O2 S
NameMETHIONINE
ChEMBLCHEMBL42336
DrugBankDB00134
ZINCZINC000001532529
PDB chain5v1t Chain A Residue 604 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5v1t Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		G160 E161 T185 T186 S210
Binding residue
(residue number reindexed from 1)		G160 E161 T185 T186 S210
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding

View graph for
Molecular Function
External links
PDB RCSB:5v1t, PDBe:5v1t, PDBj:5v1t
PDBsum5v1t
PubMed28893989
UniProtA0A0Z8EWX1

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