Structure of PDB 5n0u Chain A Binding Site BS05

Receptor Information
>5n0u Chain A (length=391) Species: 72120 (Omphalotus olearius) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNK
NCVDLYQYYDNGKSALNTYTQMSELMVREVRKGLDVVGVFYGHPGVFVNP
SHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLI
RDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHP
VVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASN
LDIIRRLELLPAGQVPDKKARIYPANQWEPDVPEVEPYRPSDQAAIAQLA
DHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTP
QERAALELGDSWAIRCAMKNMPSSLLDAARPWVIVVGVIGV
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5n0u Chain A Residue 905 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5n0u A molecular mechanism for the enzymatic methylation of nitrogen atoms within peptide bonds.
Resolution1.68 Å
Binding residue
(original residue number in PDB)		G102 H109
Binding residue
(residue number reindexed from 1)		G95 H102
Annotation score4
Enzymatic activity
Enzyme Commision number 2.1.1.-
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
Biological Process
GO:0032259 methylation

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:5n0u, PDBe:5n0u, PDBj:5n0u
PDBsum5n0u
PubMed30151425
UniProtA0A2R2JFI5|OPHMA_OMPOL Methyltransferase/ribosomally synthesized cyclic peptide omphalotin A precursor ophMA (Gene Name=ophMA)

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