Structure of PDB 5m0r Chain A Binding Site BS05

Receptor Information
>5m0r Chain A (length=276) Species: 36374 (Visna/maedi virus EV1 KV1772) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WIENIPLAEEEHNKWHQDAVSLHLEFGIPRTAAEDIVQQCDVCQENKMPS
TLRGSNKRGIDHWQVDYTHYEDKIILVWVETNSGLIYAERVKGETGQEFR
VQTMKWYAMFAPKSLQSDNGPAFVAESTQLLMKYLGIEHTTGIPWNPQSQ
ALVERTHQTLKNTLEKLIPMFNAFESALAGTLITLNIKRKGGLGTSPMDI
FIFNKEQQRIQQQSKSKQEKIRFCYYRTRKRGHPGEWQGPTQVLWGGDGA
IVVKDRGTDRYLVIANKDVKFIPPPK
Ligand information
>5m0r Chain T (length=41) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caccggagcggatctcgcagtcgaccaccctaatcaagttt
Receptor-Ligand Complex Structure
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PDB5m0r A supramolecular assembly mediates lentiviral DNA integration.
Resolution8.2 Å
Binding residue
(original residue number in PDB)		H69 P147 Q148 E154 R155 Q158 K161
Binding residue
(residue number reindexed from 1)		H69 P147 Q148 E154 R155 Q158 K161
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.4: ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:5m0r, PDBe:5m0r, PDBj:5m0r
PDBsum5m0r
PubMed28059770
UniProtP35956|POL_VILVK Gag-Pol polyprotein (Gene Name=pol)

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