Structure of PDB 5ije Chain A Binding Site BS05

Receptor Information
>5ije Chain A (length=581) Species: 9796 (Equus caballus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HKSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKK
CAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECF
LTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPE
LLFHAEEYKADFTECCPADDKLACLIPKLDALKERILLSSAKERLKCSSF
QNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLEC
ADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLP
ALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTY
EATLEKCCAEADPPACYRTVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDF
QNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHL
ALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFK
AETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSA
FVAKCCGAEDKEACFAEEGPKLVASSQLALA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5ije Chain A Residue 613 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5ije Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		E441 R444
Binding residue
(residue number reindexed from 1)		E439 R442
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005504 fatty acid binding
GO:0008289 lipid binding
GO:0015643 toxic substance binding
GO:0019825 oxygen binding
GO:0030170 pyridoxal phosphate binding
GO:0046872 metal ion binding
GO:1903981 enterobactin binding
Biological Process
GO:0009267 cellular response to starvation
GO:0051902 negative regulation of mitochondrial depolarization
GO:0072732 cellular response to calcium ion starvation
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ije, PDBe:5ije, PDBj:5ije
PDBsum5ije
PubMed28567254
UniProtP35747|ALBU_HORSE Albumin (Gene Name=ALB)

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