Structure of PDB 5ejk Chain A Binding Site BS05

Receptor Information
>5ejk Chain A (length=269) Species: 11888 (Rous sarcoma virus - Prague C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLREAKDLHTALHIGPRALSKASNISMQQAREVVQTCPHCNSAPALEAGV
NPRGLGPLQIWQTDFTLEPRMAPRSWLAVTVDTASSAIVVTQHGRVTSVA
VQHHWATAIAVMGRPKAIKTDNGSCFTSKSTREWMARWGIAHTTGIPGNS
QGQAMVERANRMMKDKIRVLAEGDGFMKRIPTSKQGEMMAKAMYALNHFE
RGENTKTPIQKHWRPTVLTEGPPVKIRIETGEWEKGWNVLVWGRGYAAVK
NRDTDKVIWVPSRKVKPDI
Ligand information
Receptor-Ligand Complex Structure
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PDB5ejk Crystal structure of the Rous sarcoma virus intasome.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		V50 N51 P52 R53 T144 G145 Q151 A154 M155 R158 M162 G202 E203 R244 Y246
Binding residue
(residue number reindexed from 1)		V50 N51 P52 R53 T144 G145 Q151 A154 M155 R158 M162 G202 E203 R244 Y246
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:5ejk, PDBe:5ejk, PDBj:5ejk
PDBsum5ejk
PubMed26887497
UniProtP03354|POL_RSVP Gag-Pol polyprotein (Gene Name=gag-pol)

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