Structure of PDB 5a68 Chain A Binding Site BS05

Receptor Information
>5a68 Chain A (length=203) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAMEVEVKLRLLTAAAHLRLTTLLTPYHLKTLHQRNTFFDTPKNDLSLRR
AVLRLRFLQNAPSPPRCIVSLKAKPTLANGISRVEEDEEEIEYWIGKECV
ESPAKLSDIGSRVLKRVKEEYGFNDFLGFVCLGGFENVRNVYEWRGVKLE
VDETKYDFGNCYEIECETEEPERVKTMIEEFLTEEKIEFSNSDMTKFAVF
RSG
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain5a68 Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5a68 Structural Determinants for Substrate Binding and Catalysis in Triphosphate Tunnel Metalloenzymes.
Resolution1.67 Å
Binding residue
(original residue number in PDB)		K6 T199 K200
Binding residue
(residue number reindexed from 1)		K8 T195 K196
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.1.-
3.6.1.25: triphosphatase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016462 pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0050355 inorganic triphosphate phosphatase activity
Biological Process
GO:0048364 root development
Cellular Component
GO:0005634 nucleus
GO:0005680 anaphase-promoting complex
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5a68, PDBe:5a68, PDBj:5a68
PDBsum5a68
PubMed26221030
UniProtQ9SIY3|TTM3_ARATH Triphosphate tunnel metalloenzyme 3 (Gene Name=TTM3)

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