Structure of PDB 4tvd Chain A Binding Site BS05

Receptor Information
>4tvd Chain A (length=1032) Species: 33967 (Leuconostoc mesenteroides subsp. mesenteroides) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLRQDSNGKLRYFDLTTGIQAKGQFVTIGQETYYFSKDHGDAQLLPMVTE
GHYGTWVYRDQNNTILKGLQNINGTLQFFDPYTGEQLKGGVAKYDDKLFY
FESGKGNLVSTVAGDYQDGHYISQDGQTRYADKQNQLVKGLVTVNGALQY
FDNATGNQIKNQQVIVDGKTYYFDDKGNGEYLFTNTLDSTNAFSTKNVAF
NHDSSSFDHTVDGFLTADTWYRPKSILANGTTWRDSTDKDMRPLITVWWP
NKNVQVNYLNFMKANGLLTTAAQYTLHSDQYDLNQAAQDVQVAIERRIAS
EHGTDWLQKLLFESQNNNPSFVKQQFIWNKDSEYHGGGDAWFQGGYLKYG
NNPLTPTTNSDYRQPGNAFDFLLANDVDNSNPVVQAENLNWLHYLMNFGT
ITAGQDDANFDSIRIDAVDFIHNDTIQRTYDYLRDAYQVQQSEAKANQHI
SLVEAGLDAGTSTIHNDALIESNLREAATLSLTNEPGKNKPLTNMLQDVD
GGTLITDHTQNSTENQATPNYSIIHAHDKGVQEKVGAAITDATGADWTNF
TDEQLKAGLELFYKDQRATNKKYNSYNIPSIYALMLTNKDTVPRMYYGDM
YQDDGQYMANKSIYYDALVSLMTARKSYVSGGQTMSVDNHGLLKSVRFGK
DAMTANDLGTSATRTEGLGVIIGNDPKLQLNDSDKVTLDMGAAHKNQKYR
AVILTTRDGLATFNSDQAPTAWTNDQGTLTFSNQEINGQDNTQIRGVANP
QVSGYLAVWVPVGASDNQDARTAATTTENHDGKVLHSNAALDSNLIYEGF
SNFQPKATTHDELTNVVIAKNADVFNNWGITSFEMAPQYRSSGDHTFLDS
TIDNGYAFTDRYDLGFNTPTKYGTDGDLRATIQALHHANMQVMADVVDNQ
VYNLPGKEVVSATRAGVYGNDDATGFGTQLYVTNSVGGGQYQEKYAGQYL
EALKAKYPDLFEGKAYDYWYKNYANDGSNPYYTLSHGDRESIPADVAIKQ
WSAKYMNGTNVLGNGMGYVLKDWHNGQYFKLD
Ligand information
Ligand IDBGC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-VFUOTHLCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.7.6C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namebeta-D-glucopyranose;
beta-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL1614854
DrugBankDB02379
ZINCZINC000003833800
PDB chain4tvd Chain A Residue 2905 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4tvd Structural Insights into the Carbohydrate Binding Ability of an alpha-(12) Branching Sucrase from Glycoside Hydrolase Family 70.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		E1895 S1896 E1973 Y1974 Y2128
Binding residue
(residue number reindexed from 1)		E102 S103 E180 Y181 Y334
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.1.5: dextransucrase.
Gene Ontology
Molecular Function
GO:0046527 glucosyltransferase activity
Biological Process
GO:0009250 glucan biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4tvd, PDBe:4tvd, PDBj:4tvd
PDBsum4tvd
PubMed26865636
UniProtG8XR50

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