Structure of PDB 3ubh Chain A Binding Site BS05

Receptor Information
>3ubh Chain A (length=409) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RAVRPTKRIEFTEADGDTEGKSVFQLEKETDKETFKIRDDNPWVTVETNG
AVRVKKKWDYEELGPEKTIDFWVIITNHNAGIKYTDNQRVIILVKDVNDE
PPYFINRPLPMQAVVQLNAPPNTPVFTLQARDPDTDHNIHYFIVRDRTGG
RFEVDERSGVVRTRGTDLFQLDMEYVLYVKAEDQNGKVRRFQSTPEERLS
IVGGKRAPQFYMPSYEAEIPENQKKDSDIISIKAKSFADREIRYTLKAQG
QGAGTFNIGPTSGIVKLAKELDFEDLRQPHVYSLIVTATEDSGGFSTSVD
LTIRVTDVNDNAPKFELPDYQAHNVDEDIPLGTSILRVKAMDSDSGSNAE
IEYLVSDDHFAVDSNGIIVNNKQLDADNNNAYYEFIVTAKDKGEPPKSGV
ATVRVYTKN
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3ubh Chain A Residue 856 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3ubh Crystal structures of Drosophila N-cadherin ectodomain regions reveal a widely used class of Ca2+-free interdomain linkers.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		E662 E715 D748 V749 D751 D785
Binding residue
(residue number reindexed from 1)		E221 E274 D307 V308 D310 D344
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3ubh, PDBe:3ubh, PDBj:3ubh
PDBsum3ubh
PubMed22171007
UniProtO15943|CADN_DROME Neural-cadherin (Gene Name=CadN)

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