Structure of PDB 2z4t Chain A Binding Site BS05

Receptor Information
>2z4t Chain A (length=493) Species: 426532 (Photobacterium sp. JT-ISH-224) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TQSIIKNDINKTIIDEEYVNLEPINQSNISFTKHSWVQTCGTQQLLTEQN
KESISLSVVAPRLDDDEKYCFDFNGVSNKGEKYITKVTLNVVAPSLEVYV
DHASLPTLQQLMDIIKSEEENPTAQRYIAWGRIVPTDEQMKELNITSFAL
INNHTPADLVQEIVKQAQTKHRLNVKLSSNTAHSFDNLVPILKELNSFNN
VTVTNIDLYDDGSAEYVNLYNWRDTLNKTDNLKIGKDYLEDVINGINEDT
SNTGTSSVYNWQKLYPANYHFLRKDYLTLEPSLHELRDYIGDSLKQMQWD
GFKKFNSKQQELFLSIVNFDKQKLQNEYNSSNLPNFVFTGTTVWAGNHER
EYYAKQQINVINNAINESSPHYLGNSYDLFFKGHPGGGIINTLIMQNYPS
MVDIPSKISFEVLMMTDMLPDAVAGIASSLYFTIPAEKIKFIVFTSTETI
TDRETALRSPLVQVMIKLGIVKEENVLFWADLPNCETGVCIAV
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain2z4t Chain A Residue 4001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2z4t Crystal structure of Vibrionaceae Photobacterium sp. JT-ISH-224 alpha2,6-sialyltransferase in a ternary complex with donor product CMP and acceptor substrate lactose: catalytic mechanism and substrate recognition
Resolution2.5 Å
Binding residue
(original residue number in PDB)		V492 K493 N496
Binding residue
(residue number reindexed from 1)		V471 K472 N475
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:2z4t, PDBe:2z4t, PDBj:2z4t
PDBsum2z4t
PubMed17962295
UniProtA8QYL1

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