Structure of PDB 1lb3 Chain A Binding Site BS05

Receptor Information
>1lb3 Chain A (length=167) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQIRQNYSTEVEAAVNRLVNLHLRASYTYLSLGFFFDRDDVALEGVGHFF
RELAEEKREGAERLLEFQNDRGGRALFQDVQKPSQDEWGKTQEAMEAALA
MEKNLNQALLDLHALGSARADPHLCDFLESHYLDKEVKLIKKMGNHLTNL
RRVASLGEYLFERLTLK
Ligand information
Ligand IDGOL
InChIInChI=1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2
InChIKeyPEDCQBHIVMGVHV-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C(C(CO)O)O
ACDLabs 12.01
CACTVS 3.370		OCC(O)CO
FormulaC3 H8 O3
NameGLYCEROL;
GLYCERIN;
PROPANE-1,2,3-TRIOL
ChEMBLCHEMBL692
DrugBankDB09462
ZINCZINC000000895048
PDB chain1lb3 Chain A Residue 189 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1lb3 Structural description of the active sites of mouse L-chain ferritin at 1.2A resolution
Resolution1.21 Å
Binding residue
(original residue number in PDB)		F39 R56
Binding residue
(residue number reindexed from 1)		F34 R51
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0008199 ferric iron binding
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005776 autophagosome
GO:0031410 cytoplasmic vesicle
GO:0044754 autolysosome
GO:0070288 ferritin complex
GO:0071682 endocytic vesicle lumen

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Cellular Component
External links
PDB RCSB:1lb3, PDBe:1lb3, PDBj:1lb3
PDBsum1lb3
PubMed12459904
UniProtP29391|FRIL1_MOUSE Ferritin light chain 1 (Gene Name=Ftl1)

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