Structure of PDB 1k7g Chain A Binding Site BS05

Receptor Information
>1k7g Chain A (length=455) Species: 556 (Dickeya chrysanthemi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSVYDFLRYHDRGDGLTVNGKTSYSIDQAAAQITRENVSWNGTNVFGKSA
NLTFKFLQSVSSIPSGDTGFVKFNAEQIEQAKLSLQSWSDVANLTFTEVT
GNKSANITFGNYTRDASGNLDYGTQAYAYYPGNYQGAGSSWYNYNQSNIR
NPGSEEYGRQTFTHEIGHALGLAHPGEYNAGEGDPSYNDAVYAEDSYQFS
IMSYWGENETGADYNGHYGGAPMIDDIAAIQRLYGANMTTRTGDSVYGFN
SNTDRDFYTATDSSKALIFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSD
VGGLKGNVSIAHGVTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGA
GADTLYGGAGRDTFVYGSGQDSTVAAYDWIADFQKGIDKIDLSAFRNEGQ
LSFVQDQFTGKGQEVMLQWDAANSITNLWLHEAGHSSVDFLVRIVGQAAQ
SDIIV
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1k7g Chain A Residue 484 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1k7g Protease C of Erwinia chrysanthemi: The Crystal Structure and Role of Amino Acids Y228 and E189
Resolution2.0 Å
Binding residue
(original residue number in PDB)		G364 A365 G366 D368 G381 G382 A383 D386
Binding residue
(residue number reindexed from 1)		G340 A341 G342 D344 G357 G358 A359 D362
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.24.40: serralysin.
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0005509 calcium ion binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0031012 extracellular matrix

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1k7g, PDBe:1k7g, PDBj:1k7g
PDBsum1k7g
PubMed11718553
UniProtP16317|PRTC_DICCH Serralysin C (Gene Name=prtC)

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