Structure of PDB 1a73 Chain A Binding Site BS05

Receptor Information
>1a73 Chain A (length=162) Species: 5791 (Physarum polycephalum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALTNAQILAVIDSWEETVGQFPVITHHVPLGGGLQGTLHCYEIPLAAPYG
VGFAKNGPTRWQYKRTINQVVHRWGSHTVPFLLEPDNINGKTCTASHLCH
NTRCHNPLHLCWESLDDNKGRNWCPGPNGGCVHAVVCLRQGPLYGPGATV
AGPQQRGSHFVV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1a73 Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1a73 DNA binding and cleavage by the nuclear intron-encoded homing endonuclease I-PpoI.
Resolution1.8 Å
Binding residue
(original residue number in PDB)
C41 C100 C105 H110
Binding residue
(residue number reindexed from 1)
C40 C99 C104 H109
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) N119
Catalytic site (residue number reindexed from 1) N118
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0006314 intron homing

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Molecular Function

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Biological Process
External links
PDB RCSB:1a73, PDBe:1a73, PDBj:1a73
PDBsum1a73
PubMed9665136
UniProtQ94702|PPO1_PHYPO Intron-encoded endonuclease I-PpoI

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