Structure of PDB 7unw Chain x Binding Site BS04

Receptor Information
>7unw Chain x (length=593) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HGFQNPTGPIVREVNIGETITVAELAAQMSVKGAEVVKFMFKMGSPVTIN
QVLDQETAQLVAEELGHKVKLVSENALEEQLAESLKFEGEAVTRAPVVTV
MGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETERGMVTFLDTP
GHAAFTAMRARGAQATDIVILVVAADDGVMPQTQEAVQHAKAAGVPIVVA
VNKIDKPEANPDNIKNGLAALDVIPEEWGGDAPFVPVSAKLGTGVDELLE
AVLLQAEVLELKATPSAPGRGVVVESRLDKGRGPVATVLVQDGTLRQGDM
VLVGINYGRVRAMLDENGKPIKEAGPSIPVEILGLDGTPDAGDEMTVVAD
EKKAREVALFRQGKFREVKLARAHAGKLENIFENMGQEEKKTLNIVLKAD
VRGSLEALQGSLSGLGNDEVQVRVVGGGVGGITESDANLALASNAVLFGF
NVRADAGARKIVEAEGLDMRYYNVIYDIIEDVKKALTGMLGSDLRENILG
IAEVRDVFRSPKFGAIAGCMVTEGMVHRNRPIRVLRDDVVIFEGELESLR
RFKDDVAEVRAGMECGIGVKSYNDVKVGDKIEVFEKVEVARSL
Ligand information
Ligand IDFME
InChIInChI=1S/C6H11NO3S/c1-11-3-2-5(6(9)10)7-4-8/h4-5H,2-3H2,1H3,(H,7,8)(H,9,10)/t5-/m0/s1
InChIKeyPYUSHNKNPOHWEZ-YFKPBYRVSA-N
SMILES
SoftwareSMILES
CACTVS 3.341CSCC[C@H](NC=O)C(O)=O
CACTVS 3.341CSCC[CH](NC=O)C(O)=O
ACDLabs 10.04O=CNC(C(=O)O)CCSC
OpenEye OEToolkits 1.5.0CSCCC(C(=O)O)NC=O
OpenEye OEToolkits 1.5.0CSCC[C@@H](C(=O)O)NC=O
FormulaC6 H11 N O3 S
NameN-FORMYLMETHIONINE
ChEMBL
DrugBankDB04464
ZINCZINC000001529464
PDB chain7unw Chain v Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7unw Compact IF2 allows initiator tRNA accommodation into the P site and gates the ribosome to elongation
Resolution2.6 Å
Binding residue
(original residue number in PDB)		R798 F799 C812
Binding residue
(residue number reindexed from 1)		R551 F552 C565
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003743 translation initiation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7unw, PDBe:7unw, PDBj:7unw
PDBsum7unw
PubMed
UniProtQ9HV55|IF2_PSEAE Translation initiation factor IF-2 (Gene Name=infB)

[Back to BioLiP]