Structure of PDB 7unv Chain x Binding Site BS04

Receptor Information
>7unv Chain x (length=593) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HGFQNPTGPIVREVNIGETITVAELAAQMSVKGAEVVKFMFKMGSPVTIN
QVLDQETAQLVAEELGHKVKLVSENALEEQLAESLKFEGEAVTRAPVVTV
MGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETERGMVTFLDTP
GHAAFTAMRARGAQATDIVILVVAADDGVMPQTQEAVQHAKAAGVPIVVA
VNKIDKPEANPDNIKNGLAALDVIPEEWGGDAPFVPVSAKLGTGVDELLE
AVLLQAEVLELKATPSAPGRGVVVESRLDKGRGPVATVLVQDGTLRQGDM
VLVGINYGRVRAMLDENGKPIKEAGPSIPVEILGLDGTPDAGDEMTVVAD
EKKAREVALFRQGKFREVKLARAHAGKLENIFENMGQEEKKTLNIVLKAD
VRGSLEALQGSLSGLGNDEVQVRVVGGGVGGITESDANLALASNAVLFGF
NVRADAGARKIVEAEGLDMRYYNVIYDIIEDVKKALTGMLGSDLRENILG
IAEVRDVFRSPKFGAIAGCMVTEGMVHRNRPIRVLRDDVVIFEGELESLR
RFKDDVAEVRAGMECGIGVKSYNDVKVGDKIEVFEKVEVARSL
Ligand information
Ligand IDFME
InChIInChI=1S/C6H11NO3S/c1-11-3-2-5(6(9)10)7-4-8/h4-5H,2-3H2,1H3,(H,7,8)(H,9,10)/t5-/m0/s1
InChIKeyPYUSHNKNPOHWEZ-YFKPBYRVSA-N
SMILES
SoftwareSMILES
CACTVS 3.341CSCC[C@H](NC=O)C(O)=O
CACTVS 3.341CSCC[CH](NC=O)C(O)=O
ACDLabs 10.04O=CNC(C(=O)O)CCSC
OpenEye OEToolkits 1.5.0CSCCC(C(=O)O)NC=O
OpenEye OEToolkits 1.5.0CSCC[C@@H](C(=O)O)NC=O
FormulaC6 H11 N O3 S
NameN-FORMYLMETHIONINE
ChEMBL
DrugBankDB04464
ZINCZINC000001529464
PDB chain7unv Chain v Residue 102 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7unv Compact IF2 allows initiator tRNA accommodation into the P site and gates the ribosome to elongation
Resolution2.7 Å
Binding residue
(original residue number in PDB)		R798 F799
Binding residue
(residue number reindexed from 1)		R551 F552
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003743 translation initiation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7unv, PDBe:7unv, PDBj:7unv
PDBsum7unv
PubMed
UniProtQ9HV55|IF2_PSEAE Translation initiation factor IF-2 (Gene Name=infB)

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