Structure of PDB 8wao Chain o Binding Site BS04

Receptor Information
>8wao Chain o (length=1452) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDP
RQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCV
CFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEHGGCG
RYQPRIRRSGLELYAEWKHVNEDSQEKKILLSPERVHEIFKRISDEECFV
LGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVK
INNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRP
LKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIA
ANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKP
SDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLN
LSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVM
GIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPL
WTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGEL
IMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGH
TIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQ
TFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVI
AVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTE
FFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQ
VVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQ
EDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLR
MIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQE
NATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGE
MVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPK
TPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTV
VAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKI
NAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFL
RCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWI
LETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHV
ISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEET
VDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGME
IP
Ligand information
>8wao Chain Y (length=73) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgtaggcacgtctgctcggctcgaagtagatgaacctgatgaagcacaac
cacccccttttataggcgccctt
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8wao Structural Visualization of de novo Transcription Initiation.
Resolution6.4 Å
Binding residue
(original residue number in PDB)		K346 A855 Y859 R1416 E1433
Binding residue
(residue number reindexed from 1)		K311 A820 Y824 R1381 E1398
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0031981 nuclear lumen
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8wao, PDBe:8wao, PDBj:8wao
PDBsum8wao
PubMed38127763
UniProtA0A8D1DPV6

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