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Receptor Information

>5t5h Chain f (length=397) Species: 5693 (Trypanosoma cruzi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

EHPRHGHLGFLPRKRSRQIRGRVRSFPKDDPSQKPHLTSFMVFKAGMTHI
VRDVDRPGSKVNKKEVVEPVTILEAPPMVVVGIVGYRQTPVGHKTIGTVW
AHHTSVEFRRRFYKNWKQSAQLAFTKRKQFARTTEGRLAEARTLKAFAKK
ADIIRVVAHTQLRKLRNNRVGVKKAHVSEIQINGGTIAEKIELAKSLLEK
EVRIDSIFQQSETCDVCAVTKGHGFTGVVKRWGVACLPRKTHRGLRKVAC
IGAWHPARVMYTVARAGQHGYHHRTHLNKKIYQLGRAVSMEPNQATTTYD
LTAKSITPMGGFVGYGTVRNDYIMLKGSVAGPRRRVITLRRPMAPQTSRK
LTEQITLKFIDTSSKIGHGRFQTKKEKSQWFGPLKKDRIRREERLRK

>5t5h Chain H (length=91) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cacgucccucuccaaacgagagaacaugcaugggcuggcaugagcgcgug
gggccccgaggcgcugaaccuugaggccucaugcugggacu

...<<<<<<<<<.......>>>>....<<<<<<<<.<<.....<<<...<
<<..>>>....>>>....>>.....>>>.>>>>>.>>>>>.

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5t5h Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit.
Resolution	2.54 Å
Binding residue (original residue number in PDB)	R21 R116 R117 Y119 K120 N121 K123 Q124 S125 A126 N174 R175 G177 V178 K179 K180 K227 G228 G230 F231 Q274 Y277 M315 G316 V319 G320 G322 R325 P338 R340 R341 S370 I372 G373 K380 K383 F387 L390 K391 R394
Binding residue (residue number reindexed from 1)	R15 R110 R111 Y113 K114 N115 K117 Q118 S119 A120 N168 R169 G171 V172 K173 K174 K221 G222 G224 F225 Q268 Y271 M309 G310 V313 G314 G316 R319 P332 R334 R335 S364 I366 G367 K374 K377 F381 L384 K385 R388

Enzyme Commision number

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome

PDB	RCSB:5t5h, PDBe:5t5h, PDBj:5t5h
PDBsum	5t5h
PubMed	27791004
UniProt	V5B599

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Structure of PDB 5t5h Chain f Binding Site BS04