Structure of PDB 6tmf Chain d Binding Site BS04

Receptor Information
>6tmf Chain d (length=582) Species: 2287 (Saccharolobus solfataricus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRVAVINYDFCKPDKCNLECINFCPVDRSGGKAIELSEIVKGKPVIYEET
CIGCGICVKKCPYEAISIVNLPDELEGEVIHRYKVNGFKLFGLPTPKNNT
ILGVLGKNGVGKTTVLKILAGEIIPNFGDPNSKVGKDEVLKRFRGKEIYN
YFKELYSNELKIVHKIQYVEYASKFLKGTVNEILTKIDERGKKDEVKELL
NMTNLWNKDANILSGGGLQRLLVAASLLREADVYIFDAPSSYLDVRERMN
MAKAIRELLKNKYVIVVDHDLIVLDYLTDLIHIIYGESSVYGRVSKSYAA
RVGINNFLKGYLPAENMKIRPDEIKFMLKTKMKWTKIIKKLGDFQLVVDN
GEAKEGEIIGILGPNGIGKTTFARILVGEITADEGSVTPEKQILSYKPQR
IFPNYDGTVQQYLENASKDALSTSSWFFEEVTKRLNLHRLLESNVNDLSG
GELQKLYIAATLAKEADLYVLDAPSSYLDVEERYIVAKAIKRVTRERKAV
TFIIDHDLSIHDYIADRIIVFKGEPEKAGLATSPVTLKTGMNEFLRELEV
TFRRDAETGRPRVNKIGSYLDRVQKERGDYYS
Ligand information
Ligand IDANP
InChIInChI=1S/C10H17N6O12P3/c11-8-5-9(13-2-12-8)16(3-14-5)10-7(18)6(17)4(27-10)1-26-31(24,25)28-30(22,23)15-29(19,20)21/h2-4,6-7,10,17-18H,1H2,(H,24,25)(H2,11,12,13)(H4,15,19,20,21,22,23)/t4-,6-,7-,10-/m1/s1
InChIKeyPVKSNHVPLWYQGJ-KQYNXXCUSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(NP(=O)(O)O)O)O)O)N
CACTVS 3.370Nc1ncnc2n(cnc12)[CH]3O[CH](CO[P](O)(=O)O[P](O)(=O)N[P](O)(O)=O)[CH](O)[CH]3O
CACTVS 3.370Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO[P](O)(=O)O[P](O)(=O)N[P](O)(O)=O)[C@@H](O)[C@H]3O
ACDLabs 12.01O=P(O)(O)NP(=O)(O)OP(=O)(O)OCC3OC(n2cnc1c(ncnc12)N)C(O)C3O
OpenEye OEToolkits 1.7.0c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)O[P@@](=O)(NP(=O)(O)O)O)O)O)N
FormulaC10 H17 N6 O12 P3
NamePHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
ChEMBLCHEMBL1230989
DrugBank
ZINCZINC000008660410
PDB chain6tmf Chain d Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6tmf Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		Y83 F88 N108 G109 G111 K112 T113 T114 Q167 H269 D459 S461 G462 G463 E464
Binding residue
(residue number reindexed from 1)		Y83 F88 N108 G109 G111 K112 T113 T114 Q167 H269 D447 S449 G450 G451 E452
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016491 oxidoreductase activity
GO:0016887 ATP hydrolysis activity
GO:0043024 ribosomal small subunit binding
GO:0046872 metal ion binding
Biological Process
GO:0006413 translational initiation
GO:0006415 translational termination

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6tmf, PDBe:6tmf, PDBj:6tmf
PDBsum6tmf
PubMed32064661
UniProtQ980K5

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