Structure of PDB 7ums Chain c Binding Site BS04

Receptor Information
>7ums Chain c (length=260) Species: 10912 (Rotavirus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LNIPITGSMDTVYSNSTREEVFLTSTLCLYYPTEASTQISDGEWKDSLSQ
MFLIKGWPTGSVYFKEYSNIVDFSVDPQLYCDYNLVLMKYDQSLELDMSE
LADLILNEWLCNPMDITLYYYQQSGESNKWISMGSSCTVKVCPLNTQTLG
IGCQTTNVDSFETVAENEKLAIVDVVDGINHKINLTTTTCTIRNCKKLGP
RENVAVIQVGGANILDITADPTTNPQIERMMRVNWKRWWQVFYTIVDYIN
QIVQVMSKRS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7ums Chain c Residue 506 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7ums Rotavirus VP4 Epitope of a Broadly Neutralizing Human Antibody Defined by Its Structure Bound with an Attenuated-Strain Virion.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		D270 T272 D274 T277
Binding residue
(residue number reindexed from 1)		D216 T218 D220 T223
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Cellular Component
GO:0016020 membrane
GO:0019028 viral capsid
GO:0039621 T=13 icosahedral viral capsid
GO:0039624 viral outer capsid
GO:0044165 host cell endoplasmic reticulum
GO:0044166 host cell endoplasmic reticulum lumen

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:7ums, PDBe:7ums, PDBj:7ums
PDBsum7ums
PubMed35924923
UniProtB1NP55

[Back to BioLiP]