Structure of PDB 6ywe Chain XX Binding Site BS04

Receptor Information
>6ywe Chain XX (length=408) Species: 5141 (Neurospora crassa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QKLRFKKTKKSGKPPLPGERKAYRKKIVLSNNNALPVPGLETLRPNDLAK
QDNVGSVKALPEDVVDALRAMEAFKPTQCWGIFRQPSVLIRQETVDLTKK
MKAAGADGKTIRMVIEGNRVTGKSLLLLQAMTHAFMNDWVVLHIPEAQEL
TTAVTEYAPIENSPLWTQPTYTLKLLQSFKRANEKVLSRMNTVYSHADLP
QIIPVNSPLLQLINSAKEADGAWTVFQALWRELNAENVPGRPPILFSLDG
LAHIMKVSDYRNPAFELIHSHDLALVKLFTDCLSGATVMPNGGAVLGATT
RGNSPRSASMELAIAQREAEKAGEKEVPQRDPYSKKYDDRVEAVMKSVEI
LRLKGVSKTEARGLLEYWAASGMLKKRVDESMVSEKWTLSGNGVVGEMER
ASLLTMKA
Ligand information
Ligand IDATP
InChIInChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChIKeyZKHQWZAMYRWXGA-KQYNXXCUSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[CH]3O[CH](CO[P](O)(=O)O[P](O)(=O)O[P](O)(O)=O)[CH](O)[CH]3O
ACDLabs 10.04O=P(O)(O)OP(=O)(O)OP(=O)(O)OCC3OC(n2cnc1c(ncnc12)N)C(O)C3O
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@@](=O)(O)O[P@](=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)O[P](O)(O)=O)[C@@H](O)[C@H]3O
FormulaC10 H16 N5 O13 P3
NameADENOSINE-5'-TRIPHOSPHATE
ChEMBLCHEMBL14249
DrugBankDB00171
ZINCZINC000004261765
PDB chain6ywe Chain XX Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ywe Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi.
Resolution2.99 Å
Binding residue
(original residue number in PDB)		C140 L150 R180 G183 K184 S185 L186 T361 R362 V456 E460
Binding residue
(residue number reindexed from 1)		C79 L89 R119 G122 K123 S124 L125 T300 R301 V395 E399
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6ywe, PDBe:6ywe, PDBj:6ywe
PDBsum6ywe
PubMed33056988
UniProtQ7SD06|RT23_NEUCR Small ribosomal subunit protein mS29 (Gene Name=rsm23)

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