Structure of PDB 6az3 Chain T Binding Site BS04

Receptor Information
>6az3 Chain T (length=154) Species: 5661 (Leishmania donovani) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
THYSRKPQVSSKSAKAKVSDLRCHYKNTFETANVINGMPLRKAQQLYRQV
LAKTRCIPFKRYNGKIGRTAQAKEWGQTKGRWPRKSVVAMMSLLKNAEAN
AIEKGLDPNQMVIKHVQVDQAARMRRRTYRAHGRITPYMCSPCHVQLFMS
EKKE
Ligand information
>6az3 Chain 5 (length=97) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uacgucccucuccaaacgagagaacaugcaugggcuggcaugagcggggg
gcucgucccgaggcgcugaaccuugaggccucaugcucagggacaca
...<<<<<<<<<.......>>>>....<<<<<<<<.<<.....<<<...<
<......>>....>>>....>>.....>>>.>>>>>...>>>>>...
Receptor-Ligand Complex Structure
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PDB6az3 Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		K43 Q46 Q50 T55 R69 A71 Q72 K74 E75
Binding residue
(residue number reindexed from 1)		K42 Q45 Q49 T54 R68 A70 Q71 K73 E74
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6az3, PDBe:6az3, PDBj:6az3
PDBsum6az3
PubMed29150609
UniProtA0A3S7WY02

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