Structure of PDB 6fc7 Chain L Binding Site BS04

Receptor Information
>6fc7 Chain L (length=276) Species: 35619 (Streptomyces griseoflavus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AGAAPAGGEVRRVTMYAERLAGGQMGYGLEKGKASIPGPLIELNEGDTLH
VEFENTMDVPVSLHVHGLDYEISSDGTKQNKSHVEPGGTRTYTWRTHEPG
RRADGTWRAGSAGYWHYHDHVVGTEFGTGGIRNGLYGPVIVRRKGDVLPD
ATHTIVFNDMTINNRPAHTGPNFEATVGDRVEIVMITHGEYYHTFHMHGH
RWADNRTGMLTGPDDPSQVIDNKICGPADSFGFQIIAGEGVGAGAWMYHC
HVQSHSDMGMVGLFLVKKPDGTIPGY
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain6fc7 Chain K Residue 405 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6fc7 Investigations of Accessibility of T2/T3 Copper Center of Two-Domain Laccase fromStreptomyces griseoflavusAc-993.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		H235 H237
Binding residue
(residue number reindexed from 1)		H196 H198
Annotation score1
Enzymatic activity
Enzyme Commision number 1.10.3.2: laccase.
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0052716 hydroquinone:oxygen oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:6fc7, PDBe:6fc7, PDBj:6fc7
PDBsum6fc7
PubMed31261802
UniProtA0A0M4FJ81

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