Structure of PDB 8sqw Chain K Binding Site BS04

Receptor Information
>8sqw Chain K (length=236) Species: 243233 (Methylococcus capsulatus str. Bath) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LLDKKWLTFALAIYTVFYLWVRWYEGVYGWSAGLDSFAPEFETYWMNFLY
TEIVLEIVTASILWGYLWKTRDRNLAALTPREELRRNFTHLVWLVAYAWA
IYWGASYFTEQDGTWHQTIVRDTDFTPSHIIEFYLSYPIYIITGFAAFIY
AKTRLPFFAKGISLPYLVLVVGPFMILPNVGLNEWGHTFWFMEELFVAPL
HYGFVIFGWLALAVMGTLTQTFYSFAQGGLGQSLCE
Ligand information
Ligand IDETF
InChIInChI=1S/C2H3F3O/c3-2(4,5)1-6/h6H,1H2
InChIKeyRHQDFWAXVIIEBN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341OCC(F)(F)F
ACDLabs 10.04FC(F)(F)CO
OpenEye OEToolkits 1.5.0C(C(F)(F)F)O
FormulaC2 H3 F3 O
NameTRIFLUOROETHANOL
ChEMBLCHEMBL116675
DrugBankDB03226
ZINCZINC000003860799
PDB chain8sqw Chain K Residue 311 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8sqw Product analogue binding identifies the copper active site of particulate methane monooyxgenase
Resolution2.16 Å
Binding residue
(original residue number in PDB)		D156 E176 N227 F240 H245
Binding residue
(residue number reindexed from 1)		D112 E132 N183 F196 H201
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.13.25: methane monooxygenase (soluble).
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0015049 methane monooxygenase [NAD(P)H] activity
GO:0046872 metal ion binding
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:8sqw, PDBe:8sqw, PDBj:8sqw
PDBsum8sqw
PubMed38187819
UniProtQ603F1

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