Structure of PDB 5akm Chain K Binding Site BS04

Receptor Information
>5akm Chain K (length=178) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NENVSGISAYLLGLIISDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIA
PLMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNM
REQIAFIKGLYVAEGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHL
DDHRHGVYVLNISLRDRIKFVHTILSSH
Ligand information
Receptor-Ligand Complex Structure
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PDB5akm Engineering a Nickase on the Homing Endonuclease I-Dmoi Scaffold.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
N32 R33 S34 E35 Y36 R37 S67 K68 Q70 D75 R81 S83 S84 K85 E117 W128 D155 H158 V160
Binding residue
(residue number reindexed from 1)
N29 R30 S31 E32 Y33 R34 S64 K65 Q67 D72 R78 S80 S81 K82 E114 W125 D152 H155 V157
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0006314 intron homing
GO:0016539 intein-mediated protein splicing

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Molecular Function

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Biological Process
External links
PDB RCSB:5akm, PDBe:5akm, PDBj:5akm
PDBsum5akm
PubMed26045557
UniProtP21505|DMO1_DESMO Homing endonuclease I-DmoI

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