Structure of PDB 8w2r Chain I Binding Site BS04

Receptor Information
>8w2r Chain I (length=258) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHG
QVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLL
KLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVIE
SMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVD
IIATDIQTKELQKQITKIQNFRVYYRGPAKLLWKGEGAVVIQDNSDIKVV
PRRKAKII
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8w2r HIV-1 integrase assembles multiple species of stable synaptic complex intasomes that are active for concerted DNA integration in vitro.
Resolution3.23 Å
Binding residue
(original residue number in PDB)		T66 H67 E152 K156 K159
Binding residue
(residue number reindexed from 1)		T64 H65 E150 K154 K157
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:8w2r, PDBe:8w2r, PDBj:8w2r
PDBsum8w2r
PubMed38582148
UniProtP12497|POL_HV1N5 Gag-Pol polyprotein (Gene Name=gag-pol)

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